Vita C
Price: $45.00
DESCRIPTION
Vitamin C (L-ascorbic acid), specially buffered with calcium.
FUNCTIONS
Vitamin C (ascorbic acid) has numerous biological functions. Foremost,
it is essential for the synthesis of
collagen and glycosaminoglycans which are the building materials
of all connective tissues, such as
skin, blood vessels, tendons, joint cartilage and bone. Vitamin
C is the required coenzyme for two groups
of enzymes that catalyze the crosslinking of collagen fibers -
lysyl hydroxylases and prolyl hydroxylases.
As such, vitamin C is essential for normal wound healing and capillary
health. It also participates in the
biosynthesis of carnitine, serotonin, and certain neurotransmitters,
including norepinephrine.
Vitamin C is among the most powerful antioxidants in humans and
animals. It is a water-soluble, chainbreaking antioxidant that
reacts directly with superoxide, hydroxyl radicals, and singlet
oxygen.
Laboratory studies show that vitamin C completely protects lipids
in plasma and low-density lipoprotein
(LDL) against atherogenic peroxidative damage. In addition, vitamin
C interacts with glutathione and
alpha-lipoic acid, and regenerates vitamin E. The antioxidant
functions of vitamin C appear to have
clinical significance in providing protection from free radical
damage to the eyes, lungs, blood and the
immune system.
Vitamin C is absorbed in the small intestine by a sodium-dependent
transport process that is intake
dependent. At normal dietary intakes of 60 to 100 mg, up to 80
or 90% of the vitamin C is absorbed. At
higher intakes, absorption becomes less efficient.
Absorption efficiency and vitamin C utilization may be greatly
enhanced during conditions of physiological stress, such as trauma
or infection.
INDICATIONS
Vitamin C may be a useful dietary supplement for individuals wishing
to increase their intake of the
antioxidant action of vitamin C.
DOSAGE
Each Tablet Contains:
Vitamin C .................................................1,000
mg
SUGGESTED USE
Adults take 1 tablet daily with meals or as directed by physician.
SIDE EFFECTS
No adverse side effects reported.
STORAGE
Store in a cool, dry place, away from direct light. Keep out of
reach of children.
REFERENCES
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Hughes DA. Effects of dietary antioxidants on the immune function
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Paolisso G, Tagliamonte MR, Rizzo MR, et al. Oxidative stress
and
advancing age: results in healthy centenarians. J Am Geriatr Soc
1998;46:833-8.
Park E, Wagenbichler P, Elmadfa I. Effects of multivitamin/mineral
supplementation, at nutritional doses, on plasma antioxidant status
and
DNA damage estimated by sister chromatid exchanges in lymphocytes
in pregnant women. Int J Vitam Nutr Res 1999;69:396-402.
Ushakova T, Melkonyan H, Nikonova L, et al. Modification of gene
expression by dietary antioxidants in radiation- induced apoptosis
of
mice splenocytes. Free Radic Biol Med 1999;26:887-91.
Victor VV, Guayerbas N, Puerto M, et al. Ascorbic acid modulates
in vitro the function of macrophages from mice with endotoxic
shock. Immunopharmacology 2000;46:89-101.